MPEG-DASH is the international-standard counterpart to HLS: adaptive segmented streaming described by an XML manifest (MPD). It is the usual carrier for Widevine- and PlayReady-protected content on Chrome, Firefox, Edge, Android, and smart TVs, using CENC encryption. Safari and iOS do not support DASH natively.
MPEG-DASH (Dynamic Adaptive Streaming over HTTP) is the international-standard counterpart to HLS. Like HLS it delivers adaptive, segmented streaming, but it is described by an XML manifest called an MPD rather than an m3u8 playlist.
The MPD describes the available renditions and segments, and the player selects quality based on bandwidth, just as in HLS. DASH is the usual carrier for Widevine- and PlayReady-protected content on Chrome, Firefox, Edge, Android, and many smart TVs, using CENC common encryption to signal multiple DRMs from one encrypted copy.
You generally do not choose DASH or HLS by hand. A capable provider packages your content into whichever the viewer's device needs, often from a single CMAF encode, and applies the matching DRM automatically.